Document Detail

Absence of the ductus venosus with direct connection between the umbilical vein and right atrium.
MedLine Citation:
PMID:  11370268     Owner:  NLM     Status:  MEDLINE    
Abnormalities of the ductus venosus are rare. We present the case of a dichorionic, diamniotic twin pregnancy in which complete absence of the ductus venosus, with direct communication between the umbilical vein and right atrium, was detected in one infant on antenatal ultrasonography. Autopsy confirmed the aberrant course of the umbilical vein, which also had an abnormal histological structure. Associated congenital anomalies included an ostium secundum type atrial septal defect, absent inferior vena cava, single left pulmonary vein, stenosed right pulmonary artery, proliferation of the hepatic arterioles with reduction of portal venules, and a duplex ureter. The literature is reviewed and pathogenesis relevant to this case is discussed.
G Langman; H Wainwright; L Matthews
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  4     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-05-23     Completed Date:  2001-09-27     Revised Date:  2006-05-08    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  298-303     Citation Subset:  IM    
Department of Anatomical Pathology, Groote Schuur Hospital and University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa.
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MeSH Terms
Abnormalities, Multiple / ultrasonography
Actins / analysis
Diseases in Twins*
Fatal Outcome
Heart Atria / abnormalities*,  ultrasonography
Heart Defects, Congenital / pathology,  ultrasonography
Portal System / abnormalities
Twins, Dizygotic
Ultrasonography, Prenatal
Umbilical Veins / abnormalities*,  ultrasonography
Vena Cava, Inferior / abnormalities*,  ultrasonography
Reg. No./Substance:

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