| Absence of cystathionase in human fetal liver: is cystine essential? | |
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MedLine Citation:
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PMID: 5465366 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cystathionase activity is not measurable in the livers of 24 human fetuses and 3 premature infants, and the concentration of cystathionine in the liver is higher than that of the brain. The placenta does not subserve the trans-sulfuration function. Cystine (or cysteine) thus may be an essential amino acid in the immature human. |
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Authors:
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J A Sturman; G Gaull; N C Raiha |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 169 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1970 Jul |
Date Detail:
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Created Date: 1970-10-05 Completed Date: 1970-10-05 Revised Date: 2011-12-07 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 74-6 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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metabolism* Brain / embryology, enzymology Cystine / metabolism* Dietary Proteins Female Fetus / metabolism* Homocysteine / metabolism Humans Hydro-Lyases / metabolism* Infant Nutritional Physiological Phenomena Infant, Newborn Infant, Premature Liver / embryology, enzymology*, metabolism* Methionine / blood Placenta / metabolism Pregnancy Transferases / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Dietary Proteins; 454-28-4/Homocysteine; 56-89-3/Cystine; 63-68-3/Methionine; EC 2.-/Transferases; EC 4.2.1.-/Hydro-Lyases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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