Document Detail


Absence of clonidine-induced food intake in hamsters.
MedLine Citation:
PMID:  3786365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous studies support an interaction between noradrenergic and opiate systems in the control of food intake. For example, in both rats and rabbits, food intake stimulated by the noradrenergic agent clonidine is reduced by opiate antagonists. The purpose of the present study was to determine whether or not clonidine stimulated the food intake of non-food-deprived hamsters, a species which appears to lack an opiate-sensitive feeding system. Hamsters fed a chow diet did not increase their food intake when injected with clonidine in doses ranging from 0.05 to 0.25 mg/kg. Furthermore, the animals did not increase their intake of sunflower seeds, a preferred diet for hamsters.
Authors:
N L Katz; T Brne; J Bolin; R F Schlemmer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  25     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-01-22     Completed Date:  1987-01-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1107-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Clonidine / pharmacology*
Cricetinae
Energy Intake / drug effects
Feeding Behavior / drug effects*
Food Preferences
Male
Mesocricetus
Species Specificity
Chemical
Reg. No./Substance:
4205-90-7/Clonidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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