Document Detail

Absence of circulating microemboli in patients with lone atrial fibrillation.
MedLine Citation:
PMID:  10491817     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation (AF) is a well-recognized independent risk factor of ischemic stroke. The aim of this study was to investigate the amount of microembolic signals (MES) in 15 patients with 'lone' AF representing the subgroup of AF patients with the lowest lifelong risk of stroke. All patients had been put on effective anticoagulation due to a scheduled electric cardioversion. Additional cardiac and arterial sources of embolism were excluded by echocardiography and extracranial color-coded duplex sonography of the carotid arteries. Unilateral one-hour transcranial Doppler monitorings revealed complete absence of MES in this series. This observation fits the concept that the amount of microembolisation is related to the risk of manifest thromboembolism. Further studies on this patient group treated with less intensive antihemostatic therapy should be undertaken to define more clearly the disease-specific microembolic activity.
D G Nabavi; A Allroggen; H Reinecke; G Schulte-Altedorneburg; D W Droste; G Breithardt; E B Ringelstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurological research     Volume:  21     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-12-10     Completed Date:  1999-12-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  566-8     Citation Subset:  IM    
Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.
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MeSH Terms
Atrial Fibrillation / complications*
Intracranial Embolism / etiology,  physiopathology,  ultrasonography*
Middle Aged
Middle Cerebral Artery / ultrasonography
Risk Assessment
Ultrasonography, Doppler, Transcranial

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