Document Detail


Abscisic acid regulation of heterophylly in Marsilea quadrifolia L.: effects of R-(-) and S-(+) isomers.
MedLine Citation:
PMID:  16203756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The plant hormone abscisic acid (ABA) induces a developmental switch in the aquatic fern Marsilea quadrifolia, causing the formation of aerial type characteristics, including the elongation of petioles and roots, a change in leaf morphology, the expansion of leaf surface area, and the shortening of the internodes. A number of ABA-responsive heterophylly (ABRH) genes are induced early during the transition. Using optically pure isomers of ABA, it was found that both the natural S-(+)-ABA and the unnatural R-(-)-ABA are capable of inducing a heterophyllous switch and regulating ABRH gene expression. When dose responses are compared, the unnatural ABA gives stronger morphogenic effects than the natural ABA at the same concentration, it is effective at lower concentrations, and its optimal concentration is also lower compared with the natural ABA. Deuterium-labelled ABA enantiomers were used to trace the fate of applied ABA and to distinguish the applied compound and its metabolites from the endogenous counterparts. In tissues, the supplied (+)-ABA was metabolized principally to dihydrophaseic acid, while the supplied (-)-ABA was converted at a slower rate to 7'-hydroxy abscisic acid. Treatment with either enantiomer resulted in increased biosynthesis of ABA, as reflected in the accumulation of endogenous dihydrophaseic acid. Taken together, these results suggest two distinct mechanisms of action for (-)-ABA: either (-)-ABA is intrinsically active, or its activity is due to the stimulation of ABA biosynthesis.
Authors:
Bai-Ling Lin; Huei-Jen Wang; Jang-Shiun Wang; L Irina Zaharia; Suzanne R Abrams
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-10-03
Journal Detail:
Title:  Journal of experimental botany     Volume:  56     ISSN:  0022-0957     ISO Abbreviation:  J. Exp. Bot.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-18     Completed Date:  2006-01-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9882906     Medline TA:  J Exp Bot     Country:  England    
Other Details:
Languages:  eng     Pagination:  2935-48     Citation Subset:  IM    
Affiliation:
Molecular and Cell Biology Division, Development Center for Biotechnology, 101 Lane 169 Konning Street, Hsichih 22143, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Abscisic Acid / chemistry*,  pharmacology*
Dose-Response Relationship, Drug
Gene Expression Regulation, Plant / drug effects
Isomerism
Marsileaceae / chemistry,  drug effects*,  growth & development*
Molecular Structure
Plant Growth Regulators / chemistry*,  pharmacology*
Plant Roots / drug effects,  growth & development
Plant Shoots / drug effects,  growth & development
Signal Transduction
Chemical
Reg. No./Substance:
0/Plant Growth Regulators; 21293-29-8/Abscisic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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