| Abrogation by subsequent feeding of antibody response including IgE, in parenterally immunized mice. | |
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MedLine Citation:
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PMID: 7069374 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have investigated the possibility of oral administration of ovalbumin (OVA) to prevent a secondary antibody response and interrupt reaginic antibody production. Repeated feeding seems necessary for both. Quality of results was dependent on the number of ingestions. Differences in abrogation of antibody response between mice strains were observed. Best results were obtained with AKR mice, good suppression was seen in C3H strain, and inconsistent results were obtained with DBA/2. 10 OVA oral doses were necessary to prevent a secondary antibody response in parenterally immunized mice, but 4 doses interrupted reaginic production in sensitized AKR mice. These results demonstrate that antigen feeding can prevent a secondary antibody response and interrupt reaginic antibody production. |
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Authors:
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S Lafont; C André; F André; J Gillon; M C Fargier |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of experimental medicine Volume: 155 ISSN: 0022-1007 ISO Abbreviation: J. Exp. Med. Publication Date: 1982 May |
Date Detail:
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Created Date: 1982-06-21 Completed Date: 1982-06-21 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985109R Medline TA: J Exp Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1573-8 Citation Subset: IM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Animals Antigens / administration & dosage*, immunology Female Immunization, Secondary* Immunoglobulin E / biosynthesis Immunoglobulins / biosynthesis* Injections, Intraperitoneal Male Mice Mice, Inbred AKR Mice, Inbred C3H Mice, Inbred DBA Ovalbumin / administration & dosage, immunology* Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 0/Immunoglobulins; 37341-29-0/Immunoglobulin E; 9006-59-1/Ovalbumin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Exp Med ISSN: 0022-1007 ISSN: 1540-9538 Publisher: The Rockefeller University Press |
Article Information Download PDF  Print publication date: Day: 1 Month: 5 Year: 1982 Volume: 155 Issue: 5 First Page: 1573 Last Page: 1578 ID: 2186674 Publisher Id: 82169275 PubMed Id: 7069374 |
| Abrogation by subsequent feeding of antibody response including IgE, in parenterally immunized mice | |
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