Document Detail


Abortion and stillbirth associated with Chlamydia psittaci var ovis in dairy goats with high titers to Toxoplasma gondii.
MedLine Citation:
PMID:  6654724     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During two consecutive breeding seasons in a brucellosis-free dairy goat herd, approximately 40% to 70% of the does (mean herd size, 14.5) had stillbirths or aborted. None of the does aborted or had stillbirths twice. In the first breeding season, 9 of 13 does aborted in the last 2 months of gestation. Three fetuses and 2 fetal placentas from 2 does were examined. Microscopic findings included severe multifocal hepatic necrosis, mild pneumonia, and mild multifocal necrosis in the brain. Cultures for Listeria monocytogenes, Chlamydia psittaci, and Coxiella burnetii were negative. Paired sera from 3 of the does that had aborted or had stillbirths were tested for antibodies to Toxoplasma gondii. On the basis of high titers, a tentative diagnosis of toxoplasmosis was made. During the following breeding season, 6 of 16 does aborted during the last 2 months of gestation. A total of 6 fetuses and 4 fetal placentas from 5 of these does were examined. Microscopic findings included infiltration of mononuclear cells around hepatic vessels and multifocal necrosis and gliosis in the brain. Chlamydia psittaci was isolated from the tissues of 1 fetus, 2 aborting does had persistent, high antibody titers against C psittaci (1:160 and 1:320), and all except 2 other does in the herd had C psittaci titers of 1:20 to 1:40. All but 2 does had T gondii titers of 1:32 to 1:4096. Evidently there was mixed infection with C psittaci and T gondii in this herd, but the former organism probably was responsible for the abortions and stillbirths.
Authors:
D E Gunson; H M Acland; D M Gillette; J E Pearson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  183     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1447-50     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Veterinary / epidemiology*,  etiology,  microbiology
Animals
Antibodies / analysis*
Chlamydophila psittaci / immunology,  isolation & purification
Disease Outbreaks / epidemiology,  veterinary*
Female
Fetal Death / epidemiology,  etiology,  microbiology,  veterinary*
Fetus / microbiology
Goats / immunology,  microbiology*
Pennsylvania
Pregnancy
Toxoplasma / immunology*
Chemical
Reg. No./Substance:
0/Antibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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