Document Detail


Abortion and perinatal sepsis associated with campylobacter infection.
MedLine Citation:
PMID:  3523697     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fetal loss or neonatal sepsis associated with campylobacter infection during pregnancy is infrequently recognized. As reported herein, one case of premature labor and neonatal sepsis due to Campylobacter fetus subspecies fetus was treated successfully with ampicillin and gentamicin. Only 19 similar cases have been cited in the literature. A review of these 19 cases reveals that the Campylobacter species involved were probably C. fetus subspecies fetus in nine instances, Campylobacter jejuni in nine, and Campylobacter coli in one. There were no significant species-related differences in clinical presentation or outcome. Eighteen of 20 pregnancies (including tht described herein) ended prematurely at 13-32 weeks of gestation. All of the mothers survived, but fetal/neonatal mortality was 80%. The pathogenesis of campylobacter infection in this situation probably involves maternal bacteremia originating from the bowel, with subsequent feto-placental involvement. Early recognition and treatment may improve fetal/neonatal outcome.
Authors:
A E Simor; M A Karmali; T Jadavji; M Roscoe
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Reviews of infectious diseases     Volume:  8     ISSN:  0162-0886     ISO Abbreviation:  Rev. Infect. Dis.     Publication Date:    1986 May-Jun
Date Detail:
Created Date:  1986-08-21     Completed Date:  1986-08-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905878     Medline TA:  Rev Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  397-402     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / etiology*
Ampicillin / therapeutic use
Campylobacter Infections / complications*,  drug therapy
Campylobacter fetus
Female
Gentamicins / therapeutic use
Humans
Infant, Newborn
Male
Obstetric Labor, Premature / etiology
Pregnancy
Sepsis / drug therapy,  etiology*
Chemical
Reg. No./Substance:
0/Gentamicins; 69-53-4/Ampicillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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