Document Detail

Abolition of ischemic response to atrial pacing following aortocoronary bypass surgery.
MedLine Citation:
PMID:  1084809     Owner:  NLM     Status:  MEDLINE    
To determine the effect of successful aortocoronary bypass surgery (ACBS) on left ventricular (LV) function, the ischemic response to right atrial pacing (RAP) was studied in 22 angina patients before and 3.8 +/- 1.1 months after surgery. All patients were free of angina after ACBS and had at least one patent graft. Before ACBS, RAP induced angina in 15 patients (Group 1) but not in 7 patients (Group 2). After ACBS, no patient had angina with RAP despite the increased maximum rate of pacing. Post-pacing LV end-diastolic pressure (LVEDP) after ACBS decreased in Group 1 from 25 +/- 6 to 15 +/- 6 mm Hg (P less than 0.01), but not in Group 2. Changes in ejection fraction, cardiac output, resting LVEDP, or LVEDP after LV angiography were not significant in either group and were therefore not useful in evaluating the result of ACBS. However the ischemic response to right atrial pacing was abolished by successful aortocoronary bypass surgery, suggesting improved myocardial perfusion during stress.
B I Jugdutt; S J Lee; R F Taylor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  54     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-09-25     Completed Date:  1976-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  225-9     Citation Subset:  AIM; IM    
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MeSH Terms
Angina Pectoris / surgery
Blood Pressure
Cardiac Output
Coronary Artery Bypass*
Coronary Circulation
Coronary Disease / physiopathology*
Electric Stimulation*
Heart Atria*
Heart Rate
Heart Ventricles / physiopathology
Middle Aged
Myocardial Contraction
Myocardial Infarction / physiopathology
Postoperative Complications / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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