| Abobotulinum toxin A and onabotulinum toxin A for masseteric hypertrophy: a split-face study in 25 Korean patients. | |
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MedLine Citation:
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PMID: 21888570 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Masseter muscle hypertrophy has been treated for cosmetic purposes using several modalities, including injection of type A or type B botulinum toxin into the masseter muscle. In this report, we compared the efficacy and safety of abobotulinum toxin A and onabotulinum toxin A treatment for masseteric hypertrophy in 25 Korean patients with a conversion factor of 2.5:1 through a controlled, split-face, and evaluator-blinded study. The mean grade of clinical improvement based on clinical assessment was 2.8 ± 0.9 for abobotulinum toxin A and 2.7 ± 0.8 for onabotulinum toxin A at eight weeks after the injection. At 12 weeks after the injection, the mean grade of clinical improvement based on clinical assessment was 2.9 ± 0.9 for abobotulinum toxin A and 2.7 ± 0.8 for onabotulinum toxin A. More pronounced improvement was observed with abobotulinum toxin A than onabotulinum toxin A in three patients (12%) at eight weeks and five patients (20%) at 12 weeks. We believe that our data can be used as an essential reference for determining the dose of type A botulinum toxin in the treatment of masseteric hypertrophy. |
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Authors:
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Soo Hyun Lee; Seong Ho Wee; Hyung-Joo Kim; Un-Cheol Yeo; Nam Ho Lee; Se Won Lee; Sung Bin Cho |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-4 |
Journal Detail:
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Title: The Journal of dermatological treatment Volume: - ISSN: 1471-1753 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8918133 Medline TA: J Dermatolog Treat Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Yonsei University College of Medicine, Department of Dermatology and Cutaneous Biology Research Institute, Seoul, Korea, Republic of. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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