| Abnormality of spontaneous lymphokine synthesis by lymphocytes of patients with connective tissue disorders. | |
| | |
MedLine Citation:
|
PMID: 437824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Forty-seven patients with various connective tissue disorders were studied to evaluate the spontaneous release of lymphocyte factors affecting the in vitro migration of guinea pig macrophages. In the assay used the lymphocytes from 8 patients produced an excessive amount of factors inhibiting macrophage migration while the lymphocytes from 12 patients produced an enhancement of migration. There were no differences in the delayed hypersensitivity skin test responses between the 2 groups of patients. The data are consistent with either an abnormality of suppressor lymphocyte function or an altered lymphocyte subpopulation relationship as a factor in this in vitro abnormality. |
| | |
Authors:
|
M Pietruszka; B S Rabin |
Related Documents
:
|
9642494 - Flow cytometric analysis of lymphocyte subsets in migraine patients during and outside ... 3050384 - Chronic lymphocytic leukemic patients, resistant to chemotherapy. 269604 - Microinterferometric measurement of dry weight of blood lymphocytes in hematologically ... 1085134 - Relationship of phytohaemagglutinin-induced lymphocyte transformation to disease activi... 16099294 - Relation between humoral pathological changes in multiple sclerosis and response to the... 16573644 - Blood 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and melatonin levels in patients ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Immunological communications Volume: 8 ISSN: 0090-0877 ISO Abbreviation: Immunol. Commun. Publication Date: 1979 |
Date Detail:
|
Created Date: 1979-07-28 Completed Date: 1979-07-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0353016 Medline TA: Immunol Commun Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 203-11 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Animals Cell Movement Collagen Diseases / immunology* Female Guinea Pigs Humans Hypersensitivity, Delayed / immunology Leukocyte Count Lymphocytes / immunology* Lymphokines / biosynthesis* Macrophages / immunology Male Middle Aged Skin Tests Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Lymphokines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Complement-fixing antibodies to chlamydia in the population (author's transl)
Next Document: Kinetics of cellular and humoral response of rabbits immunized with mycoplasma pneumoniae.