| Abnormalities of the vas deferens and epididymis in cryptorchid boys with congenital rubella. | |
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MedLine Citation:
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PMID: 45116 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cryptorchidism was present in 12% of 316 boys with congenital rubella (CR) followed by The Roosevelt Hospital Rubella Project. Eight of these patients, age 4 through 16 yr, had a recent orchiopexy, 4 on the left, 2 on the right, and 2 bilaterally. The vasoepididymal system was absent or apparently obstructed in 60% of the 10 sides. The epididymis was abnormal in 6 instances and the vas deferens in 5. Sixty-one boys of the entire series had an intravenous pyelogram (IVP) that was significantly abnormal in 18%. The 8 patients described all had a normal IVP except for 2 who had a malrotated kidney on the involved side. In 5 of the 8, a known maternal rubella infection has occurred during the first 8 wk of gestation. As the rubella virus is known to interfere with cellular growth and tissue differentiation in early pregnancy, it apparently altered the developing testis and mesonephric duct system. Similar vasoepididymal abnormalities have been described previously in patients with uncomplicated cryptorchidism, inguinal hernia, kidney defects, cystic fibrosis and male sterility. Their presence should alert the clinician to perform an IVP and also consider a diagnosis of congenital rubella. |
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Authors:
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C J Priebe; J A Holahan; P R Ziring |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 14 ISSN: 0022-3468 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 1979 Dec |
Date Detail:
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Created Date: 1980-11-20 Completed Date: 1980-11-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 834-8 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Cryptorchidism / complications* Epididymis / abnormalities* Female Humans Infant, Newborn Male Pregnancy Pregnancy Complications, Infectious Rubella / congenital* Vas Deferens / abnormalities* |
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