Document Detail


Abnormalities of lipid metabolism and methods of their correction in patients with glomerulonephritis.
MedLine Citation:
PMID:  6535784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The results of integrated estimations of a complex of lipid indices are presented. Their abnormalities are considered to be atherosclerosis risk factors in the evolution of glomerulonephritis and its different variants, types and stages. The quantitative and qualitative peculiarities of the indicated abnormalities are revealed, in particular, their major expressiveness in chronic form, nephrotic variant and in the stage of renal failure. Two aspects of correction of actual abnormalities are singled out: 1. indirect, i.e. treatment of the renal pathologic process with preparation of pathogenetic therapy (glucocorticoids, indomethacin), and 2. direct, i.e. with medications exerting a corrective influence on lipid metabolism (clofibrate, nicotinic acid, curantil). The selection of corrective methods is determined by the stage of disease and by the character of the changes in lipid metabolism.
Authors:
L A Pyrig; Melman NYa; N M Petrun; G G Nikulina; N R Gorelova
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International urology and nephrology     Volume:  16     ISSN:  0301-1623     ISO Abbreviation:  Int Urol Nephrol     Publication Date:  1984  
Date Detail:
Created Date:  1985-08-13     Completed Date:  1985-08-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0262521     Medline TA:  Int Urol Nephrol     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Arteriosclerosis / etiology,  prevention & control
Clofibrate / therapeutic use
Dipyridamole / therapeutic use
Female
Glomerulonephritis / complications*,  drug therapy,  metabolism
Humans
Hyperlipidemias / drug therapy,  etiology*,  metabolism
Lipids / blood*
Male
Middle Aged
Niacin / therapeutic use
Chemical
Reg. No./Substance:
0/Lipids; 58-32-2/Dipyridamole; 59-67-6/Niacin; 637-07-0/Clofibrate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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