Document Detail


Abnormalities associated with congenital scoliosis: a retrospective study of 226 Chinese surgical cases.
MedLine Citation:
PMID:  23197014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY DESIGN: Retrospective study of a series of 226 consecutive Chinese patients with congenital scoliosis.
OBJECTIVE: To identify the incidence of intraspinal abnormalities and other organ defects in surgical patients with congenital scoliosis in Chinese population.
SUMMARY OF BACKGROUND DATA: Previous studies have revealed high rates of intraspinal anomalies and other organ defects in patients with congenital scoliosis. The incidence of abnormalities in patients with congenital scoliosis in Chinese population has not been reported.
METHODS: A total of 226 patients with congenital scoliosis underwent surgical treatment in Peking Union Medical College Hospital between January 2005 and March 2011 were identified. A definitive diagnosis of congenital scoliosis for all patients was made. Complete data were reviewed, including medical records, plain radiograph, magnetic resonance (MR) image of the whole spine, echocardiography, and renal ultrasound. The incidence of intraspinal abnormalities and other organ defects were analyzed.
RESULTS: Intraspinal abnormalities were found in 99 (43%) patients. Diastematomyelia was identified to be the most common intraspinal pathological anomaly, which was different from the previous reports. The incidence of intraspinal anomaly in patients with failures of segmentation and mixed defects were significantly higher than those with failures of formation. Patients with thoracic hemivertebrae were found to have a higher incidence of intraspinal abnormalities than patients with lumbar hemivertebrae. Patients with intraspinal abnormality had a higher incidence of positive clinical findings than those with normal magnetic resonance imaging. However, the difference between the 2 groups was not statistically significant. Other organic defects were found in 91(40%) patients. Cardiac defects were detected in 18%, urogenital anomalies in 12%, and gastrointestinal anomalies in 5% of the patients in this study.
CONCLUSION: Diastematomyelia was found to be the most common intraspinal pathological anomaly and cardiac defects were the most common extraspinal anomaly in surgical patients with congenital scoliosis in this study. Magnetic resonance imaging, echocardiography, and ultrasound should be part of routine evaluation in all congenital cases before surgery, no matter positive clinical findings were found or not.
LEVEL OF EVIDENCE: 3.
Authors:
Jianxiong Shen; Zijia Wang; Jiaming Liu; Xuhong Xue; Guixing Qiu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Spine     Volume:  38     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-30     Completed Date:  2013-12-04     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  814-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Asian Continental Ancestry Group
Child
Child, Preschool
China / epidemiology
Comorbidity
Echocardiography
Female
Gastrointestinal Diseases / diagnosis,  epidemiology
Heart Defects, Congenital / diagnosis,  epidemiology
Humans
Incidence
Magnetic Resonance Imaging
Male
Neural Tube Defects / diagnosis,  epidemiology
Retrospective Studies
Scoliosis / congenital*,  epidemiology,  surgery*
Spine / abnormalities*,  radiography,  surgery*
Urogenital Abnormalities / diagnosis,  epidemiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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