| Abnormal spatial QRS-T angle predicts mortality in patients undergoing dobutamine stress echocardiography for suspected coronary artery disease. | |
| | |
MedLine Citation:
|
PMID: 19996961 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To investigate the association between (cardiac) mortality and spatial QRS-T angle in patients undergoing dobutamine - atropine stress echocardiography (DSE) for evaluation of known or suspected coronary disease. METHODS: Between 1990 and 2003, 2347 patients underwent DSE for evaluation of coronary disease at the Erasmus Medical Center. Echocardiographic images were analyzed offline using a 16-segment, 5-point scoring model for regional function. Twelve-lead resting ECGs were analyzed and patients were grouped in three categories according to their spatial QRS-T angle: normal (0-105 degrees), borderline (105-135 degrees), and abnormal (135-180 degrees). RESULTS: Mean age was 61+/-13 years, 66% were male, 32% had hypertension, 26% had hypercholesterolemia, 28% were smokers, and 12% were diabetic. During a mean follow-up of 7+/-3.4 years, 26.5% (623) of the patients died; 15.3% (359) died due to a cardiac cause. Abnormal QRS-T angle (135-180 degrees ) was present in 21% of the patients. Abnormal QRS-T angle was a predictor of cardiac death [hazard ratio: 3.2 (2.6-4.1)] and all-cause mortality [hazard ratio: 2.2 (1.8-2.6)]. After multivariate analysis abnormal and borderline QRS-T angle, peak wall motion score, age, male sex, history of diabetes, history of heart failure, smoking, and hypertension were independent predictors of (cardiac) death. CONCLUSION: Abnormal QRS-T angle is an independent predictor of (cardiac) death in patients undergoing DSE. Abnormal QRS-T angle should be considered as a risk factor in stable patients evaluated for coronary disease. |
| | |
Authors:
|
Jonathan A Lipton; Stefan P Nelwan; Ron T van Domburg; Jan A Kors; Abdou Elhendy; Arend F L Schinkel; Don Poldermans |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Coronary artery disease Volume: 21 ISSN: 1473-5830 ISO Abbreviation: Coron. Artery Dis. Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2009-12-22 Completed Date: 2010-03-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9011445 Medline TA: Coron Artery Dis Country: England |
Other Details:
|
Languages: eng Pagination: 26-32 Citation Subset: IM |
Affiliation:
|
Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands. j.lipton@erasmusmc.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Coronary Artery Disease / mortality*, physiopathology, ultrasonography* Echocardiography, Stress* Electrocardiography Female Hemodynamics Humans Logistic Models Male Middle Aged Predictive Value of Tests Prognosis Risk Assessment Risk Factors Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Treatment of mild-moderate calcified coronary lesions with sirolimus-eluting stent: real world data ...
Next Document: Use of exhaled breath condensate to investigate occupational lung diseases.