Document Detail

Abnormal right ventricular filling in patients with dilated cardiomyopathy.
MedLine Citation:
PMID:  8456014     Owner:  NLM     Status:  MEDLINE    
Doppler echocardiograms of the tricuspid and mitral valves were recorded along with the electrocardiogram and respiration in six patients with dilated cardiomyopathy and 20 normal children. There was significant respiratory variation in right ventricular filling in the patients with dilated cardiomyopathy. Four variables of early diastolic right ventricular filling increased with inspiration: the peak E velocity (mean increase 55%, p < 0.05), the E/total area (mean increase 32%, p < 0.001), the E/A area (mean increase 74%, p < 0.001), and peak E/A ratio (mean increase 72%, p < 0.01), whereas the peak A velocity did not change significantly and the A/total decreased (mean decrease 27%, p < 0.001). Thus, abnormalities of right ventricular filling worsened during expiration and improved with inspiration. Inspiration enhances right ventricular venous return and thus improves indices of right ventricular filling in patients with cardiomyopathy.
T W Riggs
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  14     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-16     Completed Date:  1993-04-16     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
Department of Pediatrics, William Beaumont Hospital, Royal Oak, Michigan 48073.
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MeSH Terms
Cardiomyopathy, Dilated / physiopathology,  ultrasonography*
Diastole / physiology*
Echocardiography, Doppler*
Mitral Valve / ultrasonography
Respiration / physiology*
Tricuspid Valve / ultrasonography
Ventricular Function, Left / physiology
Ventricular Function, Right / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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