Document Detail


Abnormal renovascular impedance in patients with hepatic cirrhosis: detection with duplex US.
MedLine Citation:
PMID:  8475308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to determine whether duplex ultrasound (US) can allow detection of early impairment of renal function in patients with hepatic cirrhosis. The authors calculated the pulsatility index (PI) and resistive index (RI) by using duplex US in 17 patients with cirrhosis and ascites but with normal renal function (group A), in 16 patients with cirrhosis but no ascites (group B), in 20 with chronic hepatitis (group C), in six with peritoneal carcinomatosis (group D), and in 16 healthy control subjects (group E). All patients had normal renal function on the basis of blood urea nitrogen and serum creatinine values. PI and RI were higher (P < .001) in group A patients than in others. Cirrhotic patients with ascites had renal vasoconstriction even in the absence of clinically apparent renal impairment and full-blown hepatorenal syndrome. Impaired renal perfusion plays a key role in sodium and fluid accumulation in patients with liver disease. On the basis of these results, duplex US is useful in pathophysiologic and clinical studies in such patients.
Authors:
A Colli; M Cocciolo; C Riva; E Martinez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  187     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-05-19     Completed Date:  1993-05-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  561-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Ospedale C. Borella, Milan, Italy.
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MeSH Terms
Descriptor/Qualifier:
Ascites / complications
Female
Hepatitis C / complications,  physiopathology,  ultrasonography
Hepatorenal Syndrome / etiology,  ultrasonography
Humans
Kidney / physiopathology
Liver Cirrhosis / complications,  physiopathology,  ultrasonography*
Male
Middle Aged
Peritoneal Neoplasms / physiopathology,  ultrastructure
Prospective Studies
Pulse
Renal Circulation*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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