Document Detail


Abnormal regional homogeneity of drug-naïve obsessive-compulsive patients.
MedLine Citation:
PMID:  20571458     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To explore the possible abnormal resting-state activity in patients with obsessive-compulsive disorder (OCD), the regional homogeneity (ReHo) of 22 pairs of patients and well-matched healthy controls was calculated. Compared with controls, the patients showed higher ReHo in the left anterior cingulate cortex, but lower ReHo in the left inferior temporal gyrus. These findings supported the abnormal resting-state brain activity in drug-naïve OCD patients. No significant correlations between ReHo value and four clinical characteristics were found, suggesting that abnormal ReHo might be trait-related in OCD.
Authors:
Tao Yang; Yuqi Cheng; Haijun Li; Hongyan Jiang; Chunrong Luo; Baoci Shan; Lin Xu; Xiufeng Xu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroreport     Volume:  21     ISSN:  1473-558X     ISO Abbreviation:  Neuroreport     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  England    
Other Details:
Languages:  eng     Pagination:  786-90     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, The First Affiliated Hospital of Kunming Medical College, Chinese Academy of Sciences, Kunming Institute of Zoology, The First Hospital of Kunming City, Kunming, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / pathology*
Brain Mapping
Female
Humans
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging
Male
Obsessive-Compulsive Disorder / pathology*

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