Document Detail

Abnormal pregnancy: early diagnosis by US and serum chorionic gonadotropin levels.
MedLine Citation:
PMID:  3510444     Owner:  NLM     Status:  MEDLINE    
Simultaneous sonography and quantitative serum human chorionic gonadotropin (HCG) levels from 126 women with threatened abortion were compared. Of 56 women with normal outcome, 39 (70%) had a gestation sac greater than or equal to 5 mm in mean sac diameter, and in each case the HCG level was 1,800 milli-international units (mIU/ml) or greater. The serum HCG levels strongly correlated with the gestation sac sizes to a mean sac diameter of 25 mm. Of 70 abnormal pregnancies, 31 demonstrated a gestation sac. Of these, 20 women (65%) had disproportionately low HCG levels relative to sac size, including 12 in whom the HCG level was less than 1,800 mIU/ml. One woman with an early molar pregnancy had a disproportionately elevated HCG level. Correlation of sonograms with a simultaneous measurement of serum HCG level is a useful method for evaluating threatened spontaneous abortion. A disproportionately low HCG level relative to gestation sac size is evidence for an abnormal pregnancy.
D A Nyberg; R A Filly; D L Filho; F C Laing; B S Mahony
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  158     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1986 Feb 
Date Detail:
Created Date:  1986-02-18     Completed Date:  1986-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-6     Citation Subset:  AIM; IM    
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MeSH Terms
Abortion, Spontaneous / etiology
Amnion / pathology
Chorionic Gonadotropin / blood*
Pregnancy Complications / blood,  diagnosis*
Reg. No./Substance:
0/Chorionic Gonadotropin

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