| Abnormal monocyte function in bladder cancer patients. | |
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MedLine Citation:
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PMID: 1271545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated 39 patients with various stages of bladder carcinoma to determine alterations in monocyte function. Since the monocyte plays an important role in the effector arm of the immune system defective function may explain the host's inability to destroy neoplastic cells. As a group these 39 patients demonstrated defective monocyte monocyte function. There was no correlation between tumor stage and degree of chemotactic defect. Patients with invasive carcinoma had a significant return of monocyte chemotactic response toward normal postoperatively (p less than 0.005). Monocyte function was improved also in 3 patients who received Bacillus Calmette-Guerin immunotherapy (p less than 0.05). |
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Authors:
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M S Hausman; S A Brosman |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of urology Volume: 115 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1976 May |
Date Detail:
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Created Date: 1976-08-02 Completed Date: 1976-08-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 537-41 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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BCG Vaccine
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therapeutic use Chemotaxis Humans Immunity, Cellular Monocytes / immunology*, pathology Urinary Bladder Diseases / immunology Urinary Bladder Neoplasms / immunology*, pathology, surgery, therapy |
| Chemical | |
Reg. No./Substance:
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0/BCG Vaccine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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