Document Detail


Abnormal monocyte function in bladder cancer patients.
MedLine Citation:
PMID:  1271545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated 39 patients with various stages of bladder carcinoma to determine alterations in monocyte function. Since the monocyte plays an important role in the effector arm of the immune system defective function may explain the host's inability to destroy neoplastic cells. As a group these 39 patients demonstrated defective monocyte monocyte function. There was no correlation between tumor stage and degree of chemotactic defect. Patients with invasive carcinoma had a significant return of monocyte chemotactic response toward normal postoperatively (p less than 0.005). Monocyte function was improved also in 3 patients who received Bacillus Calmette-Guerin immunotherapy (p less than 0.05).
Authors:
M S Hausman; S A Brosman
Related Documents :
23035035 - Relationship between average leucocyte telomere length and the presence or severity of ...
23625655 - Are high initial cea and ca 19-9 levels associated with the presence of k-ras mutation ...
550365 - Effects of ascorbate on leucocytes: part iii. in vitro and in vivo stimulation of abnor...
24413425 - Audiological evaluation in spinocerebellar ataxia.
990235 - Internuclear ophthalmoplegia. an electro-oculographic study of peak angular saccadic ve...
10524525 - Erosive injury to the upper gastrointestinal tract in patients receiving iron medicatio...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of urology     Volume:  115     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1976 May 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  537-41     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
BCG Vaccine / therapeutic use
Chemotaxis
Humans
Immunity, Cellular
Monocytes / immunology*,  pathology
Urinary Bladder Diseases / immunology
Urinary Bladder Neoplasms / immunology*,  pathology,  surgery,  therapy
Chemical
Reg. No./Substance:
0/BCG Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Retroperitoneal fat necrosis producing ureteral obstruction.
Next Document:  Squamous cell carcinoma of the bladder.