Document Detail


Abnormal microcirculation in brain tumours during surgery.
MedLine Citation:
PMID:  11728549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Orthogonal Polarisation Spectral imaging is a new clinical technique that uses polarised light to visualise the microcirculation of organ surfaces. We have used this technique to compare the functional microcirculatory properties of three types of brain tumour with those of the normal cortex. Meningiomas were characterised by chaotic and dilated vessels with almost no erythrocyte movement and a dark background, glioblastoma by few vessels with low flow and a background close to that of the healthy cortex, and metastases by a very dark background, almost no flow, and a chaotic vascular pattern. This technique could provide useful information about microcirculatory morphology and kinetics for diagnostic use during neurosurgery.
Authors:
K R Mathura; G J Bouma; C Ince
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Publication Detail:
Type:  Comparative Study; Letter    
Journal Detail:
Title:  Lancet     Volume:  358     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-11-30     Completed Date:  2001-12-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1698-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Brain Neoplasms / blood supply*,  surgery
Cerebral Cortex / blood supply
Diagnostic Imaging / instrumentation*
Glioblastoma / blood supply*,  surgery
Humans
Meningioma / blood supply*,  surgery
Microcirculation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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