| Abnormal maxillary trapezoid pattern in human fetal cleft lip and palate. | |
| | |
MedLine Citation:
|
PMID: 18333644 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To elucidate abnormal growth patterns of human fetal maxillae with cleft lip and palate (CLP). SUBJECT: A total of 71 fetal maxillae with CLP were obtained from aborted human fetuses. METHOD: Dimensions of the maxillary trapezoid (MT), formed by the maxillary primary growth centers (MxPGC), were taken from radiographic images. The CLP dimensions were compared with maxillary trapezoid dimensions of normal fetuses from a previous study (Lee et al., 1992). MAIN OUTCOME MEASURES: Cleft lip subjects without a cleft palate, unilateral cleft lip-alveolar cleft or cleft palate (UCL+A/UCLP), and bilateral cleft lip-alveolar cleft or cleft palate (BCL+A/BCLP) displayed abnormal MT patterns. MT abnormalities were most marked in the BCL+A/BCLP cohort. RESULTS: The MT growth of prenatal CLP maxillae was severely arrested, resulting in abnormal MT shape on palatal radiograms. BCL+A/BCLP subjects had a more protruded nasal septum than subjects with other types of CLPs, while UCL+A/UCLP subjects showed severe deviation of the protruded nasal septum toward the noncleft side. Cleft lip-only subjects also exhibited abnormal MT growth. CONCLUSION: MT is primarily involved in CLPs, so that the MT shape could be utilized as a sensitive indicator for the analysis of maxillary malformation in different types of CLPs. |
| | |
Authors:
|
Soung Min Kim; Young Joon Lee; Sang Shin Lee; Yeon Sook Kim; Suk Keun Lee; Il Bong Kim; Je Geun Chi |
Related Documents
:
|
11506054 - The institute of medicine's "dietary reference intake" for phosphorus: a critical persp... 17553734 - From the deep sea to the stars: human life support through minimal communities. 18423364 - Pericial analysis of a dental element found inside food used for human consumption. 18231604 - Chimpanzee autarky. 15147474 - The willingness to eat. an investigation of appetite among elderly people. 14980774 - Influence of carrageenan on the rheology and skin permeation of microemulsion formulati... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association Volume: 45 ISSN: 1055-6656 ISO Abbreviation: Cleft Palate Craniofac. J. Publication Date: 2008 Mar |
Date Detail:
|
Created Date: 2008-03-12 Completed Date: 2008-06-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9102566 Medline TA: Cleft Palate Craniofac J Country: United States |
Other Details:
|
Languages: eng Pagination: 131-40 Citation Subset: D; IM |
Affiliation:
|
Department of Oral and Maxillofacial Surgery, Kangnung National University, Gangeung, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alveolar Process
/
abnormalities,
embryology Case-Control Studies Cephalometry / methods Cleft Lip / embryology* Cleft Palate / embryology* Cohort Studies Gestational Age Humans Maxilla / abnormalities*, embryology Nasal Bone / embryology Nasal Septum / embryology Sphenoid Bone / embryology Zygoma / embryology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Birth prevalence of cleft lip and palate in Northern Ireland (1981 to 2000).
Next Document: Hearing thresholds in newborns with a cleft palate assessed by auditory brain stem response.