Document Detail

Abnormal leukocyte electrophoretic mobility in myotonic dystrophy.
MedLine Citation:
PMID:  512689     Owner:  NLM     Status:  MEDLINE    
Electrophoretic mobility of polymorphonuclear leukocytes (PMNs) was studied in 10 patients with myotonic dystrophy. The mobility of patients' PMNs differed significantly from that of controls. Following incubation with bacterial chemotactic factor the PMNs from patients showed significantly less change in net surface charge compared to that in controls. Our data support a leukocyte membrane defect in myotonic dystrophy.
A R Seay; F A Ziter; H R Hill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  44     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-02-28     Completed Date:  1980-02-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  13-8     Citation Subset:  IM    
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MeSH Terms
Cell Membrane
Chemotactic Factors / pharmacology
Middle Aged
Myotonic Dystrophy / blood*
Neutrophils* / drug effects
Surface Properties
Reg. No./Substance:
0/Chemotactic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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