Document Detail

Abnormal iris vasculature in myotonic dystrophy. An anterior segment angiographic study.
MedLine Citation:
PMID:  637756     Owner:  NLM     Status:  MEDLINE    
The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all nine of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne's dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy, and Friedreich's ataxia were also normal.
L Z Stern; H E Cross; A R Crebo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  35     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-05-24     Completed Date:  1978-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  224-7     Citation Subset:  AIM; IM    
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MeSH Terms
Fluorescein Angiography
Iris / blood supply*
Microcirculation / pathology*
Middle Aged
Muscular Dystrophies / pathology
Myotonic Dystrophy / pathology*

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