| Abnormal findings on dipstick urinalysis of out - patients with malaria in Abakaliki, Nigeria. | |
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MedLine Citation:
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PMID: 22297281 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background & objectives: Malaria, one of the major health challenges of the tropics affecting about 500 million people, particularly the children and pregnant women have been associated with changes in urine compositions. The present study was undertaken to document the urinary abnormalities in malaria patients based on malaria species and the level of malaria parasitaemia. Methods: Febrile patients (n = 365) with positive Giemsa - stained blood films for malaria recruited from Outpatient Department of Ebonyi State University Teaching Hospital, Abakaliki participated in the study. Patients were classified into two categories (+ and ++) based on parasite density. Apparently healthy individuals (n = 81), without malaria parasite on both thick and thin films of comparable age and gender acted as control group. Urine sample (10 ml) was collected from each participant and analysed using standard laboratory methods and techniques. Results: Seventy - four (20.3%) of the patients had Plasmodium falciparum malaria. Although all the urine parameters were higher in the malarial patients in comparison to the control, only bilirubinuria and urobilinogenuria were statistically significant (p <0.05). Also, bilirubinuria, urobilinogenuria, haematuria and proteinuria were significantly (p < 0.05) higher in P. falciparum infection than in infections with other malaria species, but only in P. falciparum infection, bilirubinuria and urobilinogenuria were significantly (p < 0.05) higher at higher parasitaemia. Conclusion: Even though positive blood film for malaria parasite remains the gold standard for the diagnosis of malaria, urinary abnormalities, such as bilirubinuria, urobilinogenuria, proteinuria and haematuria may aid in identifying patients with severe malaria parasitaemia, especially the falciparum malaria. |
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Authors:
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E I Ugwuja; N C Ugwu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of vector borne diseases Volume: 48 ISSN: 0972-9062 ISO Abbreviation: J Vector Borne Dis Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-02-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101212761 Medline TA: J Vector Borne Dis Country: India |
Other Details:
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Languages: eng Pagination: 205-9 Citation Subset: IM |
Affiliation:
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Department of Chemical Pathology, Faculty of Clinical Medicine, Ebonyi State University, Abakaliki, Nigeria. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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