Document Detail


Abnormal cortical excitability in Rett syndrome.
MedLine Citation:
PMID:  8352852     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Visual and somatosensory evoked potentials (VEPs and SEPs) were studied in 9 patients with Rett syndrome and compared with those in 6 patients with photosensitive progressive myoclonus epilepsy (PPME). In Rett syndrome, a giant III-IV amplitude of VEPs was present in 8 patients, although none exhibited giant II-III amplitudes. Four of 6 patients with Rett syndrome who demonstrated giant SEPs did not have a C reflex. Conversely, the patients with PPME demonstrated giant II-III and III-IV amplitudes in VEPs, and giant SEPs with concurrent positive C reflexes. It is concluded that the mechanism of altered cortical excitability in Rett syndrome is different from that in PPME.
Authors:
H Yamanouchi; M Kaga; M Arima
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  9     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:    1993 May-Jun
Date Detail:
Created Date:  1993-09-22     Completed Date:  1993-09-22     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  202-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, School of Medicine, Gunma University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Arousal / physiology*
Cerebral Cortex / physiopathology*
Child
Child, Preschool
Electroencephalography
Epilepsy, Complex Partial / diagnosis,  physiopathology
Epilepsy, Tonic-Clonic / diagnosis,  physiopathology
Evoked Potentials, Somatosensory / physiology
Evoked Potentials, Visual / physiology
Female
Humans
Reaction Time / physiology
Rett Syndrome / diagnosis,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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