Document Detail


Abnormal cardiac sympathetic nerve function in a patient with pheochromocytoma. An analysis using 123I metaiodobenzylguanidine scintigraphy.
MedLine Citation:
PMID:  7591331     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 23-year-old woman with pheochromocytoma had a high level of plasma norepinephrine (NE) (6039 pg/ml) and 123I metaiodobenzylguanidine (MIBG) scintigram showed decreased myocardial retention. After surgical resection, plasma norepinephrine was normalized and the myocardial retention of 123I MIBG gradually improved. These findings suggest that the possibility that the excess of circulating norepinephrine caused by pheochromocytoma could damage the cardiac sympathetic nerve function and 123I MIBG scintigraphy is a useful method of evaluating abnormalities.
Authors:
C Izumi; Y Himura; T Konishi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  50     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-12-12     Completed Date:  1995-12-12     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  189-92     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Tenri Hospital, Nara, Japan.
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MeSH Terms
Descriptor/Qualifier:
3-Iodobenzylguanidine
Adrenal Gland Neoplasms / physiopathology,  radionuclide imaging*,  surgery
Adult
Contrast Media
Female
Heart / innervation*,  radionuclide imaging
Humans
Iodine Radioisotopes / diagnostic use
Iodobenzenes / diagnostic use
Myocardial Contraction / physiology
Norepinephrine / blood
Pheochromocytoma / physiopathology,  radionuclide imaging*,  surgery
Postoperative Complications / physiopathology,  radionuclide imaging
Sympathetic Nervous System / physiopathology*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Iodine Radioisotopes; 0/Iodobenzenes; 51-41-2/Norepinephrine; 77679-27-7/3-Iodobenzylguanidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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