Document Detail

Abnormal blood viscosity in Raynaud's phenomenon.
MedLine Citation:
PMID:  58309     Owner:  NLM     Status:  MEDLINE    
The exact cause of Raynaud's phenomenon is still unknown. Since the principal feature of this condition is the precipitation of the attacks by cold, blood viscosity was measured in ten patients and in ten normal controls at 27 degrees C and 37 degrees C. The viscosity of the patients' blood was significantly higher (p less than 0.05) at 27 degrees C than that of the controls when measured at a low shear-rate (0.77 s-1). This, as well as the higher yield stress of the patients' blood, suggests that Raynaud's phenomenon may be caused by an abnormal local increase in the viscosity and yield stress of the blood in response to a fall in temperature.
K B Goyle; J A Dormandy
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Lancet     Volume:  1     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1976 Jun 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1317-8     Citation Subset:  AIM; IM    
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MeSH Terms
Agglutinins / analysis
Blood Viscosity*
Fibrinogen / analysis
Middle Aged
Raynaud Disease / blood*,  etiology
Reg. No./Substance:
0/Agglutinins; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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