Document Detail

Abnormal T-lymphocytes in lymphomatoid papulosis. A cytomorphological study with a reconstruction of a major part of the cell differentiation cycle.
MedLine Citation:
PMID:  2883764     Owner:  NLM     Status:  MEDLINE    
The abnormal cell population in lymphomatoid papulosis was studied by immunohistochemistry, light and electron microscopy in five cases. It resulted in a comprehensive description of all the main variants within the abnormal cell population. In one of the cases an irreversible intracytoplasmic process in the abnormal lymphocytes made it possible to demonstrate the derivation of lymphomatoid cells with cerebriform nuclei resembling the mycosis cells in mycosis fungoides from large histiocyte-like cells resembling the Reed-Sternberg cells in Hodgkin's disease. Variable numbers of the abnormal cells expressed Ki-1 reactivity in all four cases tested and T-cell associated antigens in two cases.
S C van der Putte; J Toonstra; W A van Vloten; J A van Unnik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Virchows Archiv. B, Cell pathology including molecular pathology     Volume:  52     ISSN:  0340-6075     ISO Abbreviation:  Virchows Arch., B, Cell Pathol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-05-27     Completed Date:  1987-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9316922     Medline TA:  Virchows Arch B Cell Pathol Incl Mol Pathol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  413-27     Citation Subset:  IM    
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MeSH Terms
Antigens, Differentiation, T-Lymphocyte
Antigens, Surface / analysis
Cell Differentiation
Immunoenzyme Techniques
Microscopy, Electron
Middle Aged
Skin Neoplasms / immunology,  pathology*
T-Lymphocytes / immunology,  pathology*,  ultrastructure
Reg. No./Substance:
0/Antigens, Differentiation, T-Lymphocyte; 0/Antigens, Surface

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