Document Detail

Abnormal Doppler velocimetry is related to adverse perinatal outcome for borderline amniotic fluid index during third trimester.
MedLine Citation:
PMID:  17100815     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the relationship between abnormal Doppler velocimetry and adverse perinatal outcomes in pregnancies with borderline amniotic fluid index (AFI). METHODS: Medical records of 3740 pregnancies with known AFI and Doppler velocimetry measurements within 2 weeks of delivery, and delivered between January 1996 and December 2003, were retrospectively analyzed. Borderline AFI was defined as 5 cm < AFI < or = 8 cm. For the umbilical artery, Doppler velocimetry was considered abnormal when the S/D ratio was greater than 3.0 or when end-diastolic flow was absent; whereas, for the uterine artery, the S/D ratio was greater than 2.6 or presence of end-systolic notch was defined as abnormal. Adverse perinatal outcomes (small for gestational age, cesarean section for fetal distress, 5 min Apgar score of less than 7, respiratory distress syndrome, NICU admission, and perinatal death) according to Doppler velocimetry in borderline AFI were evaluated. RESULTS: Compared to the normal AFI group (n = 3523), the borderline AFI group (n = 217) had significantly higher incidence of adverse perinatal outcome (28.8% vs 54.8%). There was 3-fold increase in the incidence of adverse perinatal outcome among women with the borderline AFI in comparison to normal AFI (OR, 3.00; CI, 2.27-4.00). When abnormal Doppler velocimetry was associated with borderline AFI, a 5-fold increase in the incidence of adverse perinatal outcome was noted (OR, 5.26; CI, 3.00-9.21). CONCLUSION: In the borderline AFI group, the presence of abnormal Doppler velocimetry measurement was related to increased risk of adverse perinatal outcome. Thus, borderline AFI of 5-8 cm, especially when associated with abnormal Doppler velocimetry, mandates closer antenatal surveillance.
Ja-Young Kwon; Han-Sung Kwon; Young-Han Kim; Yong-Won Park
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  32     ISSN:  1341-8076     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-14     Completed Date:  2007-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  545-9     Citation Subset:  IM    
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
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MeSH Terms
Amniotic Fluid / physiology*
Blood Flow Velocity
Infant, Newborn
Laser-Doppler Flowmetry*
Odds Ratio
Predictive Value of Tests
Pregnancy Complications / pathology
Pregnancy Outcome*
Pregnancy Trimester, Third
Retrospective Studies
Risk Factors
Sensitivity and Specificity
Umbilical Arteries / abnormalities*

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