| Ability of hematologic and serum biochemical variables to differentiate gram-negative and gram-positive mastitis in dairy cows. | |
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MedLine Citation:
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PMID: 11467599 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Medical records of 142 dairy cows with clinical mastitis were examined to determine whether hematologic or serum biochemical results could be used to distinguish between mastitis episodes caused by gram-negative bacteria (n = 78) from those caused by gram-positive bacteria (n = 64). Signalment, historic information, hematologic and serum biochemical results, milk culture results, and outcome (discharged from hospital or died) were obtained from the medical records. Cows with gram-negative mastitis had significantly (P < .01) lower blood leukocyte, segmented neutrophil, monocyte, and lymphocyte counts and had higher blood hemoglobin concentrations and hematocrits than did cows with gram-positive mastitis. Serum urea nitrogen was the only serum biochemical result associated with pathogen type, and it was higher in cows with gram-negative mastitis than in those with gram-positive mastitis. Mortality rate (25% overall) did not differ between groups. Logistic regression indicated that routine hematologic analysis (segmented neutrophil count, monocyte count, and hemoglobin concentration) was an accurate predictor of gram-negative mastitis, with a sensitivity of .93, a specificity of .89, and an overall accuracy of 91%. The values for sensitivity and specificity were higher than those previously reported for clinical tests differentiating mastitis episodes caused by gram-negative bacteria from those caused by gram-positive bacteria. Our results indicate that routine hematologic analysis is useful for predicting pathogen type in dairy cows with clinical mastitis, thereby facilitating treatment decisions. |
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Authors:
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G W Smith; P D Constable; D E Morin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: 15 ISSN: 0891-6640 ISO Abbreviation: J. Vet. Intern. Med. Publication Date: 2001 Jul-Aug |
Date Detail:
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Created Date: 2001-07-24 Completed Date: 2001-12-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 394-400 Citation Subset: IM |
Affiliation:
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Department of Veterinary Clinical Medicine, University of Illinois, Urbana 61802, USA. gw-smith@uiuc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Chemical Analysis / standards, veterinary Blood Urea Nitrogen Cattle Dairying Female Gram-Negative Bacteria / isolation & purification* Gram-Positive Bacteria / isolation & purification* Hematologic Tests / standards, veterinary Logistic Models Mastitis, Bovine / blood, diagnosis*, microbiology Milk / microbiology Predictive Value of Tests Records as Topic / veterinary Retrospective Studies Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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