Document Detail


Abdomino-phrenic dyssynergia in patients with abdominal bloating and distension.
MedLine Citation:
PMID:  21540894     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The abdomen normally accommodates intra-abdominal volume increments. Patients complaining of abdominal distension exhibit abnormal accommodation of colonic gas loads (defective contraction and excessive protrusion of the anterior wall). However, abdominal imaging demonstrated diaphragmatic descent during spontaneous episodes of bloating in patients with functional gut disorders. We aimed to establish the role of the diaphragm in abdominal distension.
METHODS: In 20 patients complaining of abdominal bloating and 15 healthy subjects, we increased the volume of the abdominal cavity with a colonic gas load, while measuring abdominal girth and electromyographic activity of the anterior abdominal muscles and of the diaphragm.
RESULTS: In healthy subjects, the colonic gas load increased girth, relaxed the diaphragm, and increased anterior wall tone. With the same gas load, patients developed significantly more abdominal distension; this was associated with paradoxical contraction of the diaphragm and relaxation of the internal oblique muscle.
CONCLUSIONS: In this experimental provocation model, abnormal accommodation of the diaphragm is involved in abdominal distension.
Authors:
Albert Villoria; Fernando Azpiroz; Emanuel Burri; Daniel Cisternas; Alfredo Soldevilla; Juan-R Malagelada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  106     ISSN:  1572-0241     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-04     Completed Date:  2011-06-28     Revised Date:  2011-08-30    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  815-9     Citation Subset:  IM    
Affiliation:
Digestive System Research Unit, University Hospital Vall d'Hebron, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Abdomen / physiopathology
Abdominal Wall / physiopathology*
Adult
Colon / physiopathology*
Female
Flatulence / physiopathology*
Gases*
Humans
Irritable Bowel Syndrome / physiopathology
Male
Middle Aged
Posture
Chemical
Reg. No./Substance:
0/Gases
Comments/Corrections
Erratum In:
Am J Gastroenterol. 2011 Jul;106(7):1405

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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