| Abdominal complications in black and Indian children with nephrotic syndrome. | |
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MedLine Citation:
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PMID: 8316921 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abdominal complications were detected and investigated in 19 (10%) of 191 children with nephrotic syndrome who experienced 35 episodes of these complications. Fourteen children were Indian with steroid-responsive nephrotic syndrome, and 5 were black, of whom 4 had membranous nephropathy and 1 focal proliferative nephritis. All had clinical features of peritonitis and hypovolaemia was frequently present. Eleven of the 35 episodes were culture-proven peritonitis (5 due to Pneumococcus, 6 due to Gram-negative bacteria) and in 24 the cultures were negative. Hypovolaemia occurred in 6 of the former group and 5 of the latter. The occurrence of these episodes bore no temporal relationship to steroid and cyclophosphamide treatment. Sixty-nine per cent of the complications appeared within the first 3 years of onset of the nephrotic syndrome and 8 of 19 patients experienced multiple episodes. In this study, hypovolaemia always occurred in the context of clinically detected peritonitis and not as a separate complication, suggesting infection together with fluid and protein losses as likely pathogenetic mechanisms. |
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Authors:
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M Adhikari; H M Coovadia |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 83 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-07-27 Completed Date: 1993-07-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: SOUTH AFRICA |
Other Details:
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Languages: eng Pagination: 253-6 Citation Subset: IM |
Affiliation:
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Department of Paediatrics and Child Health, University of Natal, Durban. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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therapeutic use Child Child, Preschool Female Humans India / ethnology Infant Infant, Newborn Male Nephrotic Syndrome / complications, ethnology* Peritonitis / drug therapy, etiology Shock / etiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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