| Abdominal compartment syndrome and acute intestinal distress syndrome. | |
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MedLine Citation:
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PMID: 22244213 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Seriously ill patients frequently present intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) as complications, and the associated mortality is very high. This review offers an update on the most controversial aspects of these entities: factors favoring their appearance, the most common causes, prognosis, and methods of measuring intra-abdominal pressure (IAP), physiopathological consequences in relation to the different organs and systems, and the currently accepted treatment measures (medical and/or surgical). Simultaneously to the strictly physical mechanisms of injury, such as direct compression of intra-abdominal organs and vessels, the transmission of IAP to other compartments, and the drop in cardiac output, a series of immune-inflammatory mediators generated in the intestine itself may also intervene. Hypoperfusion, sustained ischemia and the ischemia-reperfusion phenomenon, would act upon the microbiota, intestinal epithelium and intestinal immune system, triggering a systemic inflammatory response and multiorgan dysfunction that appears in the final stages of ACS. |
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Authors:
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A Sánchez-Miralles; G Castellanos; R Badenes; R Conejero |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-11 |
Journal Detail:
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Title: Medicina intensiva / Sociedad Espanola de Medicina Intensiva y Unidades Coronarias Volume: - ISSN: 1578-6749 ISO Abbreviation: Med Intensiva Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9207689 Medline TA: Med Intensiva Country: - |
Other Details:
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Languages: ENG; SPA Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier España, S.L. y SEMICYUC. All rights reserved. |
Affiliation:
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Servicio de Medicina Intensiva, Hospital Universitario San Juan de Alicante, Alicante, España. |
Vernacular Title:
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Síndrome compartimental abdominal y síndrome de distrés intestinal agudo. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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