Document Detail


Abdominal aortic aneurysm size regression after endovascular repair is endograft dependent.
MedLine Citation:
PMID:  12663968     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study was performed to determine whether abdominal aortic aneurysm (AAA) regression is different with various endografts after endovascular repair.
METHODS: A four-center retrospective review of size change after endovascular AAA repair was performed. Consecutive patients with at least 1-year follow-up and available imaging studies were included. Three hundred ninety patients received either the Ancure, AneuRx, Excluder, or Talent endograft. AAA size and endoleak status were recorded from computed tomography (CT) scans at the initial postoperative follow-up visit and at 1 and 2 years thereafter. AAA size was defined as the minor axis of the infrarenal aorta on the largest axial section on the two-dimensional CT scan. A change in AAA size of 0.5 cm or greater from baseline was considered clinically significant. The effect of initial size, endoleak, and type of endograft on AAA regression was analyzed.
RESULTS: Mean baseline size was significantly greater with Talent endografts and smaller with Excluder endografts. Clinically significant regression in AAA size occurred in nearly three fourths of patients with Ancure and Talent endografts at 2 years. Regression in AAA size was less frequent with the AneuRx (46%) and Excluder (44%) devices. Initial size, endoleak, and endograft type were significant predictors of regression at multivariate analysis at 1 year. However, by 2 years only endograft type was still an independent predictor of AAA shrinkage.
CONCLUSIONS: Long-term morphologic changes after endovascular aneurysm repair depend on endograft type.
Authors:
Daniel J Bertges; Kira Chow; Mark C Wyers; Doug Landsittel; Anthony V Frydrych; William Stavropoulos; Walter A Tan; Robert Y Rhee; Mark F Fillinger; Ronald M Fairman; Michel S Makaroun
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  37     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-03-28     Completed Date:  2003-05-09     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  716-23     Citation Subset:  IM    
Affiliation:
University of Pittsburgh Medical Center, Pennsylvania, USA.
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MeSH Terms
Descriptor/Qualifier:
Aortic Aneurysm, Abdominal / diagnosis*,  surgery*
Blood Vessel Prosthesis*
Blood Vessel Prosthesis Implantation / adverse effects,  instrumentation*
Body Weights and Measures / methods
Humans
Remission Induction
Retrospective Studies
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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