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Abdominal aortic aneurysm associated with systemic fungal infection in a German shepherd dog.
MedLine Citation:
PMID:  21164161     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
A 2 yr old spayed female German shepherd presented with a chief complaint of acute onset paraparesis and weight loss. At presentation, the dog was pyrexic, nonambulatory, and had generalized muscle wasting. Neurolocalization was consistent with a thoracolumbar spinal cord lesion. An abdominal ultrasound was performed and revealed a focal dilation (4 cm) of the terminal aorta with evidence of blood stasis consistent with an aortic aneurysm. The dog was euthanized shortly after admission to the hospital and a post mortem examination was performed. Fungal organisms were identified in the aortic aneurysm as well as from the thoracic vertebrae, mesenteric lymph nodes, axillary lymph nodes, spleen, kidneys, liver, lungs, and heart. Although the morphology was consistent with Candida spp., immunohistochemistry and PCR could not definitively identify the causative organism. Mycotic aortic aneurysms are a rare finding in humans and have not been previously reported in the dog. To the authors' knowledge, this is the first known report of an aortic aneurysm associated with systemic fungal infection in a dog.
Authors:
Ryan T Gershenson; Raffaele Melidone; James Sutherland-Smith; Catherine L Rogers
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-12-16
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  47     ISSN:  1547-3317     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2010-12-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  45-9     Citation Subset:  IM    
Affiliation:
Angell Animal Medical Center Department of Emergency and Critical Care, Boston, MA, USA. rgershenson@mspca.org
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