Document Detail

Abdominal wall infections with in situ mesh.
MedLine Citation:
PMID:  20583867     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Synthetic mesh is used commonly in the repair of abdominal wall hernias. Infection at the surgical site where mesh is present poses a formidable clinical problem. METHODS: The current surgical literature was reviewed to formulate accepted approaches to the management of hernia repairs with infected mesh. RESULTS: Prevention of mesh infection is best achieved by judicious use of systemic antibiotics. Topical antibiotics often are used without convincing evidence to support their value. Laparoscopic repairs have lower infection rates than open repairs. Evidence is lacking to support lower rates of infection with mesh of specific composition or with antibacterial agents that coat the mesh. The diagnosis of mesh infection is principally a clinical one. Repairs of infected mesh usually necessitate antibiotics and removal of the foreign material. Clinical judgment is required for attempts at salvaging portions of the mesh. Component separation or biological materials may be used in those circumstances for hernia repair in which large defects are created by removal of the infected synthetic material. CONCLUSIONS: Prevention of mesh infections remains the best strategy. Clinical judgment is essential in determining the degree of mesh removal. Continued clinical studies are necessary to improve the outcomes of established mesh infection in hernia repairs.
Richard D Collage; Matthew R Rosengart
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Surgical infections     Volume:  11     ISSN:  1557-8674     ISO Abbreviation:  Surg Infect (Larchmt)     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-29     Completed Date:  2010-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815642     Medline TA:  Surg Infect (Larchmt)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-8     Citation Subset:  IM    
Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
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MeSH Terms
Abdominal Wall / microbiology*,  pathology*
Anti-Bacterial Agents / therapeutic use
Antibiotic Prophylaxis / methods
Laparoscopy / methods
Surgical Mesh / adverse effects*
Surgical Wound Infection / microbiology*,  prevention & control,  surgery,  therapy*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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