Document Detail

AV nodal pathways in the R-R interval histogram of the 24-hour monitoring ECG in patients with atrial fibrillation.
MedLine Citation:
PMID:  11686908     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patients with more than one AV nodal pathway show two and more peaks in the histogram of the R-R intervals of the Holter monitoring ECG during atrial fibrillation. It was the purpose of the present study to determine the number of patients showing more than one AV nodal pathway in a larger patient group with permanent atrial fibrillation by analyzing the Holter monitoring ECG. METHODS: 250 patients with permanent atrial fibrillation during Holter monitoring ECG were studied; 203 patients had structural heart disease. The number of peaks in the R-R interval histogram of each patient was determined. The distribution of the number of peaks in the R-R interval histogram in different patient groups was analyzed. RESULTS: 153 patients (61%) had one peak, 80 patients (32%) two peaks, 13 patients (5%) three peaks, and four patients (2%) four peaks, reflecting the number of different AV nodal pathways. In the different patient groups, in the patients with or without structural heart disease, with coronary heart disease, with a history of syncope, and in patients with a mean heart rate of more than 100/min, there was no significant difference in the distribution of the number of peaks in the R-R interval histogram. CONCLUSIONS: In more than one third of all patients with permanent atrial fibrillation there are two, three, or four AV nodal pathways. It is suggested that this number of different AV nodal pathways found in the studied group can be applied to all humans. 38.8% of all patients with permanent atrial fibrillation have more than one AV nodal pathway; 6.4% of all patients with atrial fibrillation would benefit from an ablation of AV nodal pathways with shorter refractory periods for reduction of the heart rate.
P Weismüller; C Kratz; B Brandts; K Kattenbeck; H J Trappe; C Ranke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc     Volume:  6     ISSN:  1082-720X     ISO Abbreviation:  Ann Noninvasive Electrocardiol     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-11-05     Completed Date:  2002-02-15     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  9607443     Medline TA:  Ann Noninvasive Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  285-9     Citation Subset:  IM    
Department of Cardiology and Angiology, Marienhospital, University of Bochum, Hölkeskampring 40, 44625 Herne, Germany.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / physiopathology*
Atrioventricular Node / physiopathology*
Chi-Square Distribution
Cohort Studies
Electrocardiography, Ambulatory* / drug effects
Heart Rate / drug effects
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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