| The ATTRACT trial: rationale for early intervention for iliofemoral DVT. | |
| | |
MedLine Citation:
|
PMID: 20047905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The management of acute deep vein thrombosis (DVT) by medical therapy with anticoagulation has long been supported by evidence-based clinical practice guidelines outlined in the American College of Chest Physicians supplement. Early thrombus removal in patients with iliofemoral DVT has been reported to lead to improved venous valve function, improved quality of life, and decreased incidence of postthrombotic syndrome over anticoagulation alone. The ATTRACT trial will randomize patients to medical management with standard anticoagulation versus catheter-directed thrombolysis in addition to standard anticoagulation after stratification to iliofemoral versus femoropopliteal DVT in order to determine the primary outcome of postthrombotic syndrome over a 24-month follow-up. |
| | |
Authors:
|
Anthony J Comerota |
Related Documents
:
|
2862695 - Prophylaxis and management of stress ulcers. 396975 - Medical aspects of the preoperative management of aneurysms: a review. 18414285 - Medication management in older adults: a critique of concordance. 16088675 - Multidisciplinary management of sedation and analgesia in critical care. 16985925 - Aua guidelines and their impact on the management of bph: an update. 16213495 - Evidence for proprotein convertase activity in the endoplasmic reticulum/early golgi. |
Publication Detail:
|
Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-01-03 |
Journal Detail:
|
Title: Perspectives in vascular surgery and endovascular therapy Volume: 21 ISSN: 1521-5768 ISO Abbreviation: Perspect Vasc Surg Endovasc Ther Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2010-07-14 Completed Date: 2010-10-15 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100970607 Medline TA: Perspect Vasc Surg Endovasc Ther Country: United States |
Other Details:
|
Languages: eng Pagination: 221-4; quiz 224-5 Citation Subset: IM |
Affiliation:
|
Jobst Vascular Center, The Toledo Hospital, Toledo, OH 43606, USA. marilyn.gravett@promedica.org |
| Data Bank Information | |
Bank Name/Acc. No.:
|
ClinicalTrials.gov/NCT00790335 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anticoagulants
/
therapeutic use* Catheterization, Peripheral* Femoral Vein* Fibrinolytic Agents / administration & dosage* Humans Iliac Vein* Postthrombotic Syndrome / etiology, prevention & control* Research Design Thrombolytic Therapy / methods* Treatment Outcome United States Venous Thrombosis / complications, drug therapy* |
| Grant Support | |
ID/Acronym/Agency:
|
U01HL088018/HL/NHLBI NIH HHS; U01HL088476/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants; 0/Fibrinolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury.
Next Document: Superdormant spores of bacillus species germinate normally with high pressure, peptidoglycan fragmen...