| ASCRS White Paper: clinical review of intraoperative floppy-iris syndrome. | |
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MedLine Citation:
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PMID: 19027575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intraoperative floppy-iris syndrome (IFIS) is associated with the use of systemic alpha(1)-antagonists, and tamsulosin in particular. The incidence and severity of IFIS are variable; however, the syndrome is associated with a higher rate of cataract surgical complications, especially when the condition is not recognized or anticipated. Questioning cataract patients preoperatively about current or previous use of alpha(1)-antagonists is therefore important. Intraoperative floppy-iris syndrome surgical management strategies include pharmacologic measures, the use of high-viscosity ophthalmic viscosurgical devices, and mechanical dilating devices. However, sphincterotomies and pupil stretching are ineffective. Whether used alone or in combination, these small-pupil techniques improve the surgical success rate in these cases. Stopping the alpha(1)-antagonist preoperatively is of questionable value. |
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Authors:
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David F Chang; Rosa Braga-Mele; Nick Mamalis; Samuel Masket; Kevin M Miller; Louis D Nichamin; Richard B Packard; Mark Packer; |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of cataract and refractive surgery Volume: 34 ISSN: 0886-3350 ISO Abbreviation: J Cataract Refract Surg Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-25 Completed Date: 2009-02-02 Revised Date: 2009-05-26 |
Medline Journal Info:
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Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: United States |
Other Details:
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Languages: eng Pagination: 2153-62 Citation Subset: IM |
Affiliation:
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dceye@earthlink.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Antagonists
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adverse effects* Cataract Extraction* Humans Intraoperative Complications* Iris Diseases / chemically induced*, metabolism, prevention & control Male Muscle, Smooth / metabolism Prostatic Hyperplasia / drug therapy Pupil / drug effects* Receptors, Adrenergic, alpha-1 / antagonists & inhibitors, metabolism Sulfonamides / adverse effects* Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Antagonists; 0/Receptors, Adrenergic, alpha-1; 0/Sulfonamides; 106133-20-4/tamsulosin |
| Comments/Corrections | |
Comment In:
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J Cataract Refract Surg. 2009 Jun;35(6):964
[PMID:
19465267
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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