| AP@home: A Novel European Approach to Bring the Artificial Pancreas Home. | |
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MedLine Citation:
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PMID: 22226253 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The development of an artificial pancreas (AP) made huge strides from 2006 to 2008 and a large number of activities are going on in this area of research. Until now, most AP systems under development were tested only under highly controlled conditions. The aim of our project, funded by the European Union, is to develop an AP system to such a level that it can be studied under daily life conditions at the home of patients with diabetes (hence AP@home). Based on a subcutaneous-subcutaneous closed-loop strategy (i.e., glucose sensing and insulin infusion in the subcutaneous tissue), two different approaches will be taken to achieve this aim: a two-port AP system and a single-port AP system. The two-port AP system will use off-the-shelf-components for the glucose sensor and insulin pump in combination with closed-loop algorithms generated in Europe. As to the single-port AP system, two different innovative single-port systems will be developed; in this case, continuous glucose monitoring and insulin infusion will take place via a single catheter. The first clinical trials with the two-port AP system under controlled clinical conditions have started and good progress has been made in the development of the single-port AP systems. We believe that our consortium of 12 European partners, which builds on existing achievements and close cooperation between academic centers and industry, can contribute substantially to the development of an AP system that can be used by patients in daily life. |
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Authors:
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Lutz Heinemann; Carsten Benesch; J Hans Devries |
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Publication Detail:
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Type: Journal Article Date: 2011-11-01 |
Journal Detail:
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Title: Journal of diabetes science and technology Volume: 5 ISSN: 1932-2968 ISO Abbreviation: J Diabetes Sci Technol Publication Date: 2011 |
Date Detail:
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Created Date: 2012-01-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101306166 Medline TA: J Diabetes Sci Technol Country: United States |
Other Details:
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Languages: eng Pagination: 1363-72 Citation Subset: IM |
Copyright Information:
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© 2011 Diabetes Technology Society. |
Affiliation:
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Profil Institut für Stoffwechselforschung, Neuss, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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