Document Detail


APUD cells in normal and hyperplastic prostates.
MedLine Citation:
PMID:  94688     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Argyrophilia and argentaffinity, as basic properties of APUD cells, were investigated in 50 normal and hyperplastic prostates, which included both autopsy and surgical specimens from patients of various ages. Normal prostates (including glands from 3 foetuses) had 62% of argyrophil-positive granules in the glandular epithelia, while only 44% of the hyperplastic glands were positive. Argentaffin-positive cells were found in 12% of the surgical hyperplastic cases. Both argyrophil and argentaffin cells were distributed in zones, often in lobule-like shapes, lying along the basal membrane. On the basis of these findings, there is a discussion on the possible roles played by the so-called APUD cells in hyperplastic and neoplastic growths of the prostate, such as carcinoid tumours (apudomas) or endocrine-associated syndromes in the course of prostatic cancer.
Authors:
L Pollice; L Resta; G Simone
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  La Ricerca in clinica e in laboratorio     Volume:  9     ISSN:  0390-5748     ISO Abbreviation:  Ric Clin Lab     Publication Date:    1979 Jul-Sep
Date Detail:
Created Date:  1980-07-12     Completed Date:  1980-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613947     Medline TA:  Ric Clin Lab     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  273-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
APUD Cells*
Adolescent
Adult
Age Factors
Aged
Apudoma*
Cell Count
Humans
Infant
Male
Middle Aged
Prostate / cytology*,  pathology
Prostatic Hyperplasia / pathology*
Prostatic Neoplasms*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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