| The "AMA-Brazil" cooperative project: a nation-wide assessment of the clinical and epidemiological profile of AIDS-related deaths in Brazil in the antiretroviral treatment era. | |
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MedLine Citation:
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PMID: 21503518 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The objective of this study was to assess the profile of AIDS-related deaths in the post antiretroviral therapy (ART) scale up period in Brazil. A case-control study was conducted including a nationally probabilistic sample of AIDS deaths and living controls. Data were abstracted from medical records and nation-wide databases of AIDS cases, mortality, ART care, and laboratory testing. Interrupted (adjusted odds ratio--AOR 4.35, 95%CI: 3.15-6.00) or no use of ART (AOR 2.39, 95%CI: 1.57-3.65) was the strongest predictor of death, followed by late diagnosis (AOR 3.95, 95%CI: 2.68-5.82). Criterion other than CD4 < 350 had a higher likelihood of death (AOR 1.65, 95%CI: 1.14-2.40). Not receiving recommended vaccines (AOR, 1.76, 95%CI: 1.21-2.56), presenting AIDS-related diseases (AOR 2.19, 95%CI: 1.22-3.93) and tuberculosis (AOR 1.50, 95%CI: 1.14-1.97) had higher odds of death. Being an injecting drug user (IDU) had a borderline association with higher odds of death, while homo/bisexual exposure showed a protective effect. Despite remarkable successes, Brazilians continue to die of AIDS in the post-ART scale up period. Many factors contributing to continued mortality are preventable. |
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Authors:
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Maria Amelia de Sousa Mascena Veras; Manoel C A Ribeiro; Leda Fátima Jamal; Willi McFarland; Francisco Inácio Bastos; Karina Braga Ribeiro; Rita Barradas Barata; José Cassio de Moraes; Arthur L Reingold |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cadernos de saúde pública / Ministério da Saúde, Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública Volume: 27 Suppl 1 ISSN: 1678-4464 ISO Abbreviation: Cad Saude Publica Publication Date: 2011 |
Date Detail:
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Created Date: 2011-04-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8901573 Medline TA: Cad Saude Publica Country: Brazil |
Other Details:
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Languages: eng Pagination: S104-13 Citation Subset: IM |
Affiliation:
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Departamento de Medicina Social, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, Brasil. maria.veras@gmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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