Document Detail

ALPHA Glycolytic Vasculogenesis Better Correlates With MRI and CT Imaging Techniques Than the Traditional Oxygen Vasculogenesis Theory.
MedLine Citation:
PMID:  25415739     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE. Traditional vasculogenesis has many contradictions related to treatment and imaging. This occurs because cancer also uses glycolysis, which does not need oxygen or arteries. Glycolytic lactate supports many procancer processes but high levels of it inhibit glycolysis. CONCLUSION. To avoid this, lactate induces vascular growth factors that initiate glycolytic vasculogenesis ALPHA (acidic lactate sequentially induces first lymphangiogenesis, phlebogenesis, and then arteriogenesis). The sequence of vessel development is lymphatics, veins, and then arteries. Modern contrast imaging depends more on veins than arteries, which is more consistent with ALPHA than the traditional theory.
John R Haaga; Rebecca Haaga; Indravadan Patel; Zachary Love; Joseph Moulter
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  203     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  W724-34     Citation Subset:  AIM; IM    
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