| AIDS-associated Kaposi's sarcoma in Northeastern Nigeria. | |
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MedLine Citation:
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PMID: 17139404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Kaposi's sarcoma is an acquired immunodeficiency syndrome (AIDS)-defining illness, and with the size of the human immunodeficiency virus (HIV)/AIDS pandemic in sub-Saharan Africa, AIDS-related Kaposi's sarcoma (KS) are now being diagnosed more frequently, although the true incidence of HIV-associated KS is not known. The clinical presentations of AIDS-related KS varied markedly across the African continent. This article reports a series of unusual clinical presentations of the tumour in Northeastern Nigeria. METHODS: This is a prospective study carried out from September 2003 to August 2005, at the University of Maiduguri Teaching Hospital, Borno State, Northeastern Nigeria. RESULTS: 20 cases of histologically-confirmed KS were prospectively studied. There were 17 (85 percent) men and three (15 percent) women, giving a male to female ratio of 5.7:1. Their ages ranged from 21-45 (median 37) years. 18 (90 percent) of the patients were anaemic. Mean haematocrit value, CD4+ cell count and duration of symptoms for all the patients were 29.5 +/- 7.5 percent, 119.0 +/- 91.4 cells per microlitre and 3.5 +/-1.7 months, respectively. Multiple lesions were a common presentation affecting sites such as lower limbs, trunk, conjunctiva, upper limbs and rectum as well as penis, lymph node, scrotum and oropharynx. CONCLUSION: Contrary to other reports that KS is not associated with HIV infection, our study has demonstrated otherwise. This study also showed that both sexes are affected but with a male preponderance. KS is also a late presentation of the HIV/AIDS disease spectrum in our environment and has varied clinical manifestations. There is an urgent need to develop health education programmes to enhance the understanding of this disease and how it spreads, particularly among the young generation. |
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Authors:
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M B Kagu; H A Nggada; H I Garandawa; B H Askira; M A Durosinmi |
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3007894 - Lymphadenopathy related to the acquired immunodeficiency syndrome in homosexual men. 18394954 - Genetic diversity of the kaposi's sarcoma herpesvirus k1 protein in aids-ks in zimbabwe. 2678294 - Diseases of the chest in aids: ct diagnosis. 6496534 - Acquired immune deficiency syndrome. no evidence of the presence of cyclosporine. 8265234 - A method for removing an incarcerated rod. 238324 - Microsurgery in clinical urology. |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Singapore medical journal Volume: 47 ISSN: 0037-5675 ISO Abbreviation: Singapore Med J Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-12-01 Completed Date: 2007-02-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404516 Medline TA: Singapore Med J Country: Singapore |
Other Details:
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Languages: eng Pagination: 1069-74 Citation Subset: IM |
Affiliation:
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Department of Haematology, University of Maiduguri Teaching Hospital, PMB 1414, Maiduguri, Borno, Nigeria. bmk449@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications* Adult CD4 Lymphocyte Count* Female HIV-1* HIV-2* Hematocrit Hospitals, Teaching Humans Male Middle Aged Nigeria Prospective Studies Sarcoma, Kaposi / complications, pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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