| AID and partners: for better and (not) for worse. | |
| | |
MedLine Citation:
|
PMID: 21439803 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Post-rearrangement diversification of the antibody repertoire relies on a DNA editing factor, the cytidine deaminase AID. How B lymphocytes avoid generalized mutagenesis while expressing high levels of AID remained a long-standing question. Genome-wide studies of AID targeting combined to the discovery of several co-factors controlling its recruitment and its local activity shed new light on this enigma. |
| | |
Authors:
|
Sébastien Storck; Said Aoufouchi; Jean-Claude Weill; Claude-Agnès Reynaud |
Related Documents
:
|
1482863 - Can artificial neural networks provide an "expert's" view of medical students performan... 18048143 - Biomolecular autonomous solution of the hamiltonian path problem via hairpin formation. 11351833 - Problems with sexuality after sexual assault. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-23 |
Journal Detail:
|
Title: Current opinion in immunology Volume: - ISSN: 1879-0372 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8900118 Medline TA: Curr Opin Immunol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Institut National de la Santé et de la Recherche Médicale Unité 783 "Développement du système immunitaire", Université Paris Descartes, Faculté de Médecine, Site Necker-Enfants Malades, 156 rue de Vaugirard, 75730 Paris, Cedex 15, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Potential antibiotic and anti-infective effects of rhodomyrtone from Rhodomyrtus tomentosa (Aiton) H...
Next Document: Breath profiles by electronic nose correlate with systemic markers but not ozone response.