Document Detail

ACOG practice bulletin. Medical management of tubal pregnancy. Number 3, December 1998. Clinical management guidelines for obstetrician-gynecologists. American College of Obstetricians and Gynecologists.
MedLine Citation:
PMID:  10390113     Owner:  NLM     Status:  MEDLINE    
Ectopic pregnancy is a major health problem for women of reproductive age and, in the United States, is the leading cause of pregnancy-related death during the first trimester. Diagnosis and treatment of tubal pregnancy before tubal rupture occurs decreases the risk of death. Early detection may make it possible for some patients to receive medical therapy instead of surgery. Methotrexate, a folinic acid antagonist, has been used to treat patients with small unruptured tubal pregnancies. The purpose of this document is to present evidence, including risks and benefits, about methotrexate as an alternative treatment for selected ectopic pregnancies.
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Publication Detail:
Type:  Guideline; Journal Article; Practice Guideline    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  65     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-09-20     Completed Date:  1999-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  97-103     Citation Subset:  IM    
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MeSH Terms
Abortifacient Agents, Nonsteroidal / therapeutic use*
Chorionic Gonadotropin / blood
Methotrexate / therapeutic use*
Pregnancy, Tubal / diagnosis*,  drug therapy*
Progesterone / blood
Ultrasonography, Prenatal
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 0/Chorionic Gonadotropin; 57-83-0/Progesterone; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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