Document Detail

ACOG Practice Bulletin No. 77: screening for fetal chromosomal abnormalities.
MedLine Citation:
PMID:  17197615     Owner:  NLM     Status:  MEDLINE    
In the last decade, numerous markers and strategies for Down syndrome screening have been developed. Algorithms that combine ultrasound and serum markers in the first and second trimesters have been evaluated. Furthermore, the practice of using age cutoffs to determine whether women should be offered screening or invasive diagnostic testing has been challenged. The purpose of this document is to 1) present and evaluate the best available evidence for the use of ultrasonographic and serum markers for selected aneuploidy screening in pregnancy and 2) offer practical recommendations for implementing Down syndrome screening in practice.
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Publication Detail:
Type:  Journal Article; Practice Guideline    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  109     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-01     Completed Date:  2007-02-15     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-27     Citation Subset:  AIM; IM    
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MeSH Terms
Biological Markers
Chromosome Disorders / blood,  diagnosis*,  ultrasonography
Down Syndrome / blood,  diagnosis,  ultrasonography
Genetic Counseling
Genetic Testing
Health Services Accessibility
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy, Multiple
Prenatal Diagnosis / methods*
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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