Document Detail

ACE inhibitor-induced angioedema in elderly African American females requiring tracheostomy.
MedLine Citation:
PMID:  20575219     Owner:  NLM     Status:  MEDLINE    
Angioedema is a well-demarcated localized edema involving the deeper layers of the skin, subcutaneous tissue, mucosa, and submucosa. It is a well-recognized side effect of angiotensin-converting enzyme (ACE) inhibitor therapy. Prolonged angioedema is rare. In most cases, the angioedema is self-limited and responds to cessation of ACE inhibitor therapy. ACE inhibitor-related angioedema occurs more commonly in African American patients and tends to be particularly severe in elderly African American women. We report 2 cases of extremely severe angioedema of prolonged duration that required tracheostomy to stabilize the airway.
Yizhak Kupfer; Kavan Ramachandran; Sidney Tessler
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  102     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-25     Completed Date:  2010-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  529-30     Citation Subset:  IM    
SUNY Health Science Center at Brooklyn, Brooklyn, USA.
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MeSH Terms
African Americans*
Aged, 80 and over
Angioedema / chemically induced*,  complications,  surgery
Angiotensin-Converting Enzyme Inhibitors / adverse effects*,  therapeutic use
Diagnosis, Differential
Dyspnea / diagnosis,  etiology,  surgery*
Follow-Up Studies
Hypertension / drug therapy
Tracheostomy / methods*
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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