| AARC Clinical Practice Guideline. Surfactant Replacement Therapy: 2013. | |
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MedLine Citation:
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PMID: 23359726 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We searched the MEDLINE, CINAHL, and Cochrane Library databases for English-language randomized controlled trials, systematic reviews, and articles investigating surfactant replacement therapy published between January 1990 and July 2012. By inspection of titles, references having no relevance to the clinical practice guideline were eliminated. The update of this clinical practice guideline is based on 253 clinical trials and systematic reviews, and 12 articles investigating surfactant replacement therapy. The following recommendations are made following the Grading of Recommendations Assessment, Development, and Evaluation scoring system: 1: Administration of surfactant replacement therapy is strongly recommended in a clinical setting where properly trained personnel and equipment for intubation and resuscitation are readily available. 2: Prophylactic surfactant administration is recommended for neonatal respiratory distress syndrome (RDS) in which surfactant deficiency is suspected. 3: Rescue or therapeutic administration of surfactant after the initiation of mechanical ventilation in infants with clinically confirmed RDS is strongly recommended. 4: A multiple surfactant dose strategy is recommended over a single dose strategy. 5: Natural exogenous surfactant preparations are recommended over laboratory derived synthetic suspensions at this time. 6: We suggest that aerosolized delivery of surfactant not be utilized at this time. |
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Authors:
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Brian K Walsh; Brandon Daigle; Robert M Diblasi; Ruben D Restrepo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Respiratory care Volume: 58 ISSN: 0020-1324 ISO Abbreviation: Respir Care Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7510357 Medline TA: Respir Care Country: United States |
Other Details:
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Languages: eng Pagination: 367-75 Citation Subset: IM |
Affiliation:
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Children's Medical Center, Dallas, Texas. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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